Screening Workflow for Extractables Testing Using the UNIFI Scientific Information System

■ ■ A rapid and automated way to evaluate information for an unknown component (m/z) by ranking the possible elemental compositions, and searching databases for likely structures ranked based on fragmentation matching. INTRODUCTION Characterization of packaging, food contact materials, medical devices, and many other consumables used in various industries is becoming more and more important due to ever-increasing global regulations. The initial step in characterizing extractables from packaging includes targeted screening, i.e. testing the extracts for known compounds. This is a well-established process and can be performed in various ways by using analytical techniques ranging from GC-FID-MS to LC-UV-MS. However, the final packaging may have impurities present from starting materials and additional degradants such as those formed during the molding process. The structural elucidation of unknowns is typically a very complex and time-consuming process that requires the analyst to have a high level of expertise. Waters® UNIFI Scientific Information System provides a simple workflow that includes scientific library creation, multivariate statistical analysis, elucidation, and reporting. This single platform Informatics solution enables analysts to evaluate complex data in a more efficient way through simplifying data review and facilitating the decision-making process. Screening Workflow for Extractables Testing Using the UNIFI Scientific Information System